prikaz prve stranice dokumenta EPR study of lipid phase in renal cortical membrane organelles from intact and cadmium-intoxicated rats
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EPR study of lipid phase in renal cortical membrane organelles from intact and cadmium-intoxicated rats
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1718 (2005), 1-2; 44-52. https://doi.org/10.1016/j.bbamem.2005.09.022
Zuvić-Butorac, Marta; Herak-Kramberger, M Carol; Krilov, Dubravka; Sabolić, Ivan; Herak, Janko

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Zuvić Butorac, M., Herak Kramberger, M. C., Krilov, D., Sabolić, I. i Herak, J. (2005). EPR study of lipid phase in renal cortical membrane organelles from intact and cadmium-intoxicated rats. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1718. (1-2), 44-52. doi: 10.1016/j.bbamem.2005.09.022

Zuvić Butorac, Marta, et al. "EPR study of lipid phase in renal cortical membrane organelles from intact and cadmium-intoxicated rats." Biochimica et Biophysica Acta (BBA) - Biomembranes, vol. 1718, br. 1-2, 2005, str. 44-52. https://doi.org/10.1016/j.bbamem.2005.09.022

Zuvić Butorac, Marta, M Carol Herak Kramberger, Dubravka Krilov, Ivan Sabolić i Janko Herak. "EPR study of lipid phase in renal cortical membrane organelles from intact and cadmium-intoxicated rats." Biochimica et Biophysica Acta (BBA) - Biomembranes 1718, br. 1-2 (2005): 44-52. https://doi.org/10.1016/j.bbamem.2005.09.022

Zuvić Butorac, M., et al. (2005) 'EPR study of lipid phase in renal cortical membrane organelles from intact and cadmium-intoxicated rats', Biochimica et Biophysica Acta (BBA) - Biomembranes, 1718(1-2), str. 44-52. doi: 10.1016/j.bbamem.2005.09.022

Zuvić Butorac M, Herak Kramberger MC, Krilov D, Sabolić I, Herak J. EPR study of lipid phase in renal cortical membrane organelles from intact and cadmium-intoxicated rats. Biochimica et Biophysica Acta (BBA) - Biomembranes [Internet]. 12.2005. [pristupljeno 25.04.2024.];1718(1-2):44-52. doi: 10.1016/j.bbamem.2005.09.022

M. Zuvić Butorac, M. C. Herak Kramberger, D. Krilov, I. Sabolić i J. Herak, "EPR study of lipid phase in renal cortical membrane organelles from intact and cadmium-intoxicated rats", Biochimica et Biophysica Acta (BBA) - Biomembranes, vol. 1718, br. 1-2, str. 44-52, Prosinac 2005. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:193:688943. [Citirano: 25.04.2024.]

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Naslov (engleski)EPR study of lipid phase in renal cortical membrane organelles from intact and cadmium-intoxicated rats
AutorMarta Zuvić-Butorac
AutorM Carol Herak-Kramberger
AutorDubravka Krilov
AutorIvan Sabolić
AutorJanko Herak
Autorova ustanovaSveučilište u Rijeci
(Fakultet biotehnologije i razvoja lijekova)
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Fizika
Biofizika i medicinska fizika
Sažetak (engleski)
Numerous studies have demonstrated various structure/function correlations at the level of transport proteins in the kidney cell membranes and various intracellular organelles. However, characterization of the lipid phase of these membranes is rare. Here, we report the differences in lipid organization and dynamics of the brush-border membranes (BBM), basolateral membranes (BLM) and endocytotic vesicles (EV), isolated from the kidney cortex of intact rats, studied with the EPR spectroscopy of the spin-labeled membrane lipids. The EPR spectra were analyzed by comparing experimentally observed line shapes with the line shapes calculated according to the theoretical model developed for liquid crystals. In the fitting procedure, three different lipid domains were assumed, which revealed clear differences in the lipid ordering and rotational correlation times, as well as in the lipid partition of these domains in each of the three types of membranes. A similar approach, used to compare the spectroscopic characteristics of BBM from control and cadmium-intoxicated rats, showed significantly changed ordering and increased molecular mobility in the lipid phase of BBM from Cd-treated animals. As tested by an established fluorescence assay, the Cd-induced changes in the lipid mobility co localized with approximately 5-fold higher conductance of BBM for potassium, with unchanged conductance for protons.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiochimica et Biophysica Acta (BBA) - Biomembranes
Brojčani podacivol. 1718, br. 1-2, str. 44-52
p-ISSN0005-2736
DOIhttps://doi.org/10.1016/j.bbamem.2005.09.022
URN:NBNurn:nbn:hr:193:688943
Datum objave publikacije2005-12
URL dokumentahttps://www.sciencedirect.com/science/article/pii/S0005273605003135?via%3Dihub
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
RepozitorijRepozitorij Fakulteta biotehnologije i razvoja lijekova
Datum i vrijeme pohrane2018-09-30 17:55:40